منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولAssociation of CYP1A1 IIe462Val (rs1048943) Polymorphism with Breast Cancer in Iranian Women
Backgrounds and Aims: One member of the cytochrome P450 family, CYP1A1, is one of the genes involved in the metabolism of carcinogens and estrogen, which has been identified to be associated with breast cancer, as well. Considering the known effect of estrogen in different signaling pathways, disorders in these pathways will affect the risk of breast cancer. In this study, we evaluated the rela...
متن کاملrole of cyp1a1 mspi polymorphism in cyp1a1 gene with susceptibility to lung cancer in iranian patients
normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : lung cancer has remained the most prevalent malignancy worldwide. it is the fifth leading cause of cancer death in iran. nevertheless, during last few years a gradual permanent increase in its incidence has been reported. although the crucial role of tobacco smoke in lung cancer initiation has long been establ...
متن کاملCYP1A1 regulates breast cancer proliferation and survival.
Cytochrome P450-1A1 (CYP1A1) is an extrahepatic phase I metabolizing enzyme whose expression is suppressed under physiologic conditions but can be induced by substrates via the aryl hydrocarbon receptor (AhR). Recent studies have shown that the majority of breast cancer tumors constitutively express CYP1A1. These findings led us to test the hypothesis that CYP1A1 promotes breast cancer progress...
متن کاملGenetic polymorphism in ERCC5 and breast cancer risk
ERCC5 plays crucial role in excision repair DNA damage induced by UV in NER pathway. Single neuleotide polymorphism in ERCC5 were responsible for different cancers.Therefore, current study evaluated the relationship between ERCC5 (rs1047768 T>C) polymorphism and the risk of breast cancer in Pakistani population. The rs1047768 polymorphism was screened among 175 female...
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ژورنال
عنوان ژورنال: Annals of Military and Health Sciences Research
سال: 2017
ISSN: 2383-1979,2383-1960
DOI: 10.5812/amh.63399